Week 1 of the 2025 college football season features a loaded slate, including LSU at Clemson, Notre Dame at Miami and Alabama at Florida State, among others. LSU-Clemson could be a top-five matchup, as could the biggest headliner: Manning and Texas visiting Ohio State in a matchup of the 2024 national champion and our early 2025 favorite.

"First, Ohio State (No. 1 on [Mark] Schlabach's list) is obviously in despite a challenging 2025 schedule (No. 2 Texas and No. 3 Penn State at home, No. 13 Illinois and No. 21 Michigan on the road) and the requisite loss to the Wolverines," Connelly noted. "The Buckeyes will go 2-1 against the other headliners and advance at 10-2."