The sequence homology is over 95%; PTM and aggregation prediction reports are also available 100% success rate As quick as 3–4 weeks to offer required humanized antibodies Affinity evaluated by ...

It has been estimated that the human immune system can produce up to 1 quintillion different antibodies by changing the sequence of these amino acids, helping to ensure that the body can respond ...

The process is followed by computationally guided mutagenesis or evolution of the antibody sequence (hit to lead, or H2L, optimisation) to improve the binding and other properties. Although the ...

Moreover, as the gene sequence is known, it can be used time and again. “Knowing that your antibody is going to behave the same way years down the line, gives you peace of mind,” Solache adds.

While conventional antibodies are derived from hybridoma technology, the recombinant antibodies are generated by introducing a genetic sequence and encoding the antibody into the host cells like ...

The data clearly demonstrate that a single-antibody framework can harness diverse CDR sequences previously not found in combination, including CDR loops with foreign canonical structures ...

Antibody drugs have reshaped how we treat diseases. By harnessing the immune system to destroy tumours or temper excessive inflammation in autoimmune disorders, these therapeutics have become ...

Alexion Pharmaceuticals v Amgen (UPC_Coa-405/2024) and Alexion Pharmaceuticals v Samsung Bioepis NL BV (UPC_CoA-402/2024); December 20, 2024.

Monoclonal antibodies are considered the most rapidly growing class of therapeutics. Critical quality attributes such as sequence assessment, charge and size variants must be thoroughly monitored ...

The Pioneer Platform features a state-of-the-art phage display library engineered to include more than 200 billion unique sequences and capable of identifying high-affinity antibody candidates using ...