In mammals, nonhomologous end joining (NHEJ) is the primary pathway for repair of double-strand breaks (DSBs) generated by exogenous agents like ionizing radiation. It is also the only significant ...
DNA double-strand breaks (DSB) are repaired by multiple repair pathways such as non-homologous end-joining (NHEJ), homologous recombination (HR) and microhomology-mediated end joining (MMEJ). These ...