A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle Cottrell, an assistant professor of biochemistry, spotlights ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...

Double-stranded RNA (dsRNA) is a critical immunostimulatory impurity in mRNA production and poses a problem for the downstream purification methods vital to manufacturing mRNA vaccines and ...

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Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA (mRNA) while leaving others alone. This finding could contribute to the ...

The double-stranded RNA-specific adenosine deaminase enzyme family are encoded by the ADAR family genes. ADAR stands for ...

Researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines. RNA-based medicines are one of the most promising ways to fight human disease, as ...