ETS factor expression is aberrantly upregulated in solid tumours through chromosomal translocation and amplification. Activating mutations in KIT stabilize the ETV1 protein through the MEK–ERK pathway ...

Encoded full length and N-terminal-truncated proteins believed to be responsible for inducing cell transformation retain the Ets DNA-binding domain ETS gene translocations represent an early event in ...

The concept: find a COTS* motorcycle LED light dimmer that can be spliced into an auxiliary LED light array to vary the light output. We found this “Rotary LED Dimmer”, made by ADVmonster and designed ...

A protein that was thought to simply turn genes on and off now looks to be more like a cellular "dimmer switch," researchers from Huntsman Cancer Institute at the University of Utah, report in the ...

Light switches come in two types, the on/off and the variable, or dimmer switch. Might phosphorylation switches on proteins work in two ways, also? While addition of a single phosphate can often turn ...