Prince Frederik of Luxembourg, who died at 22, spoke about the rare genetic disorder he navigated in a video released by The PolG Foundation he founded.

Prince Frederik, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, has died at the age of 22. He passed away on March 1 from POLG Mitochondrial disease, a rare genetic disorder.

Luxembourg’s royal family are in mourning after the death of a young prince who had lived with a rare genetic condition. Prince Frederik died on March 1 2025 in Paris at the age of