Genome instability is a hallmark of both cancer and ageing 1,2,3,4,5,6. The genome is assaulted daily by different stresses, including both endogenous and exogenous stresses. Remarkably, activation of ...

As newborn neurons make their way through the developing brain, they must squeeze through incredibly tight spaces to reach their final destinations. Researchers discovered that this physical journey ...

Migrating newborn neurons suffer routine double-strand DNA breaks from physical stress during brain development.

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...

An illustration of light purple Cas9 enzyme being guided to light blue DNA against dark blue background. The enzyme Cas9 (top) can cause double-strand breaks in DNA (bottom). Credit: Shutterstock ...