This important study demonstrates that a peri-nuclear actomyosin network, present in some types of human cells, facilitates kinetochore-spindle attachment of chromosomes in unfavorable locations - ...

Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

When cells divide, microtubules – a dynamic network of protein filaments – form a mitotic spindle that draws the chromosomes apart and arranges them into two daughter cells. Here, plants and animals ...

Many millions of times per day, football-shaped structures called mitotic spindles form within the body's cells as they prepare to divide. The process is routine but mysterious, as the micro-mechanics ...

Adam R. Lamson, Christopher Edelmaier, Matthew A. Glaser, and Meredith D. Betterton (2019). Biophysical Journal116, 1719. bioRxiv DOI: 10.1101/419135. DOI: 10.1016/j ...

This is a preview. Log in through your library . Abstract The mitotic spindle of L strain fibroblasts, fixed with glutaraldehyde followed by osmium tetroxide, contains many 150- to 180-A tubules. They ...

Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists now examine how ...

Mitotic spindles are dynamic, self-organizing, intracellular structures that are essential for cell division. Spindles are composed of proteins, cytoskeletal elements and microtubules, which are a key ...

A normally operating mitotic spindle in C-elegan with chromosomes in red amid pipe-like microtubules in green and densely packed microtubules in yellow. Centrioles, unseen, are inside the two yellow ...