A substantial number of messenger RNAs (mRNAs) annotated as graft-mobile on the basis of RNA sequencing (RNA-seq) data lack statistical support. Known technical issues, such as RNA sequencing noise, ...

Accurate assembly of rRNA-depleted (total) RNA sequencing (RNA-seq) remains challenging because existing methods often conflate incomplete, nascent RNA with fully processed mature isoforms, leading to ...

A team of scientists led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have released one of the world's largest and most comprehensive long-read RNA sequencing datasets, addressing a ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular ...

Discover why animal models fall short in AI drug discovery and how human-first datasets and functional genomics are changing ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

New technologies advance scalable library normalization for high-throughput genomics labs and improved amplification accuracy for oncology-focused sequencing workflows where data quality is critical ...