Northwestern Medicine investigators have identified novel mechanisms regulating the development of the spinal column during embryonic development, findings that could inform new treatments for ...

Spina bifida is a developmental malformation of the spinal cord that leads to complications in several organ systems and considerable disability, even decades after repair of the anomaly. Before the ...

Spina bifida in dogs is a congenital condition that occurs when a dog's spine and spinal cord fail to develop properly during early gestation. This condition belongs to a group of disorders known as ...

Meningomyelocele, also commonly known as myelomeningocele, is a type of spina bifida. Spina bifida is a birth defect in which the spinal canal and the backbone don’t close before the baby is born.

Davin Oyundi with her son Floyce Oyier who developed spinal bifida and underwent successful correctional surgery. [Collins Oduor, Standard] Three-year-old Floyce Oyier struggles to stand on her feet.

We analyzed data from 40,771 infants with two or more major birth defects in the Texas Birth Defects Registry (TBDR; 1999–2014). We calculated adjusted observed-to-expected (O/E) ratios for all two, ...

THE mother of a four-month-old infant often breaks down in tears as she recounts the story of her daughter, who was born with ...

Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating ...

Neural tube defects are among the most challenging congenital conditions in medicine, with a devastating burden on patients, families, and health care systems. These defects arise when the neural tube ...

Spinal muscular atrophy (SMA) is a severe neurological disease caused by reduced survival of motor neuron (SMN) protein levels. There is presently no cure for the condition, although current therapies ...