Tetrodotoxin (TTX) is best known as the neurotoxin of the puffer fish, though it also appears in a range of other marine species. You might remember it from an episode of The Simpsons involving a ...

Opioids remain a mainstay of treatment for chronic and surgical pain, despite their side effects and risk for addiction and overdose. While conventional local anesthetics block pain very effectively, ...

The neurotoxin tetrodotoxin has been found for the first time in two species living out of water. Tetrodotoxin is a potent paralysis-inducing neurotoxin found in a multitude of aquatic organisms, but ...

A quicker way of making one of the world’s most potent neurotoxins could lead to novel drugs for pain relief and to a better understanding of how the body’s pain system works. Tetrodotoxin (or TTX) is ...

A man is in a critical condition in a hospital in Hong Kong after consuming puffer fish and suffering suspected tetrodotoxin poisoning. The 65-year-old man developed facial numbness, general weakness ...

The U.S. Food and Drug Administration is working with local officials to investigate a case of tetrodotoxin poisoning in Fairfax County, VA, which they suspect is linked to the consumption of imported ...

Alternatives to opioids for treating pain are sorely needed. A study in rats suggests that tetrodotoxin, properly packaged, offers a potentially safe pain block. Opioids remain a mainstay of treatment ...