The Cardinals won the toss and elected to defer, giving the 49ers the first possession of the game. On the opening kickoff, ...

Buffalo Bills wide receiver Mecole Hardman didn't have his finest moment against the Tampa Bay Buccaneers on Sunday.

The San Francisco 49ers are on the road against the Arizona Cardinals. A blowout feels too good to be true. The Cardinals are ...

The Arizona Cardinals play host to the San Francisco 49ers in Week 11 NFL action. Both teams move into this week hoping to ...

Kyle Madson of Niners Wire takes Cardinals fans behind enemy lines before the Week 11 Cardinals vs. 49ers showdown.

Bam Knight is active for the Arizona Cardinals' Week 11 game against the San Francisco 49ers and will likely lead the ...

Mac Jones went 5-3 as the 49ers starting quarterback while Brock Purdy recovered from a turf toe injury. But his time as ...

USA Today's NFL experts make their picks for a Week 11 showdown between the Arizona Cardinals and San Francisco 49ers ...

Brock Purdy returns to the San Francisco 49ers lineup in Week 12. Can he lead the Niners past the Arizona Cardinals in a ...

The Kansas City Chiefs and Denver Broncos have each released their inactive lists ahead of their big AFC West tilt on Sunday ...

Walter Nolen III, a defensive tackle out of Ole Miss, was scouted by the 49ers, who instead took Mykel Williams with the No.

Signs pointed toward CB Deommodore Lenoir not being able to play for the San Francisco 49ers on Sunday, but their inactives ...