Here are the lines, spreads and totals for all 16 games on the Week 17 slate. Football Power Index (FPI) by ESPN Analytics.

Today in Sports, December 29 - New England Patriots become 1st team in NFL history to finish regular season 16-0 ...

Justin Herbert and the Chargers look to clinch a playoff berth with a victory over the New England Patriots at Gillette ...

Which team will win the NFL Week 17 game? Check out these NFL Week 17 picks and NFL Week 17 predictions for the ...

With Arizona Cardinals right tackle Jonah Williams on the shelf again after suffering his second right knee injury of the ...

San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

Five of the seven playoff spots are taken in the AFC, with the Kansas City Chiefs clinching the conference's overall top seed with a 29-10 win over the Pittsburgh Steelers on Wednesday. In the NFC, ...

BEST BETS LOS ANGELES CHARGERS (9-6) at NEW ENGLAND PATRIOTS (3-12) LINE: L.A. Chargers by 4.5 This is a 10 a.m. start time ...

Miami Dolphins' Calais Campbell offered a message to his team through the media before the Week 17 matchup versus the ...

The latest rumor in the Chicago Bears ' coaching search is that there's mutual interest between the team and former USC ...

2008 — The Detroit Lions lose to the Green Bay Packers 31-21, making them the first team to go winless through a 16-game ...

SportsLine's advanced model has locked in its Week 17 NFL betting picks and Week 17 NFL football predictions from 10,000 ...