Polysaccharides—long chains of simple sugars—play central roles in biological systems, including supporting cell structure, storing chemical energy, and regulating cell recognition. But synthesizing ...

Hooking sugar molecules together to make strings called glycans—also known as oligosaccharides and polysaccharides—is one of synthetic chemistry’s most bedeviling challenges. Carbohydrates are ...

Pneumococcal polysaccharide conjugate vaccines prevent pneumococcal disease in infants, but their efficacy against pneumococcal community-acquired pneumonia in adults 65 years of age or older is ...

Molar mass plays a vital role in the solubility, stability and potency of polysaccharide-based vaccines. The production process includes a crucial depolymerization step to cut the polysaccharide’s ...