The 49ers are partly to blame for why Christian McCaffrey will be out at least four games and possibly more as he nurses ...

The Rams have their work cut out for them in Week 3 but they have a chance to upset the 49ers if they win these 5 matchups ...

Just as the San Francisco 49ers won’t miss seeing Aaron Donald lining up for the Los Angeles Rams on Sunday, Sean McVay won’t ...

Injuries can make or break your fantasy season. Here is the latest news on the NFL's biggest stars with injury questions ...

The San Francisco 49ers and Miami Dolphins are two teams with very different needs, and one NFL insider believes ...

Matthew Berry breaks down his Love/Hate players for Week 3 and explains to fantasy managers why their seasons aren't over ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

The San Francisco 49ers won’t have wide receiver Deebo Samuel for a couple weeks because of a calf injury he sustained late ...

With all the injury issues and slow starts surrounding the 49ers' offense, former Super Bowl-winning quarterback Steve Young ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

The San Francisco 49ers will be missing two of their biggest playmakers when they visit SoFi Stadium on Sunday to face the ...