San Francisco 49ers running back Christian McCaffrey scores his tenth touchdown of the 2025 NFL season, and second of the game, on a 9-yard reception ...

The Arizona Cardinals and San Francisco 49ers revealed their final inactives report for Week 11 - who's in, who's out?

I don’t know any other running backs that can do that, to be honest,” Brock Purdy said of Christian McCaffrey’s touchdown ...

Head coach Kyle Shanahan of the San Francisco 49ers looks on during warmups before the game against the Arizona Cardinals at ...

The 49ers head to State Farm Stadium to face the Arizona Cardinals with Brock Purdy back under center. Purdy was cleared off ...

San Francisco 49ers WR Skyy Moore sped past the Cardinals coverage unit with a 98-yard kickoff return to open the Week 11 ...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

Follow along with live updates as the San Francisco 49ers begin a crucial four-game stretch starting in Arizona against the Cardinals.

Take a look at players who have been ruled out for the San Francisco 49ers Week 11 matchup versus the Arizona Cardinals.

Mac Jones went 5-3 as the 49ers starting quarterback while Brock Purdy recovered from a turf toe injury. But his time as starter came to an end Sunday when coach Kyle Shanahan announced Purdy would ...

The 49ers and Saints, to completely different results, revealed the best way to stop the Rams' vaunted pass rush. It's called ...

49ers head coach Kyle Shanahan, during an appearance on NBC Sports 49ers Talk, had some very high praise for Pearsall amid ...