The EMBO Journal9h
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal1d
Rett syndrome: interferon-γ to the rescue?
Rett syndrome is a severe neurodevelopmental disorder in girls, underpinned by mutations in the X-linked gene MECP2. In their ...
The EMBO Journal4d
TRPC5: a new entry to the chromaffin cell’s palette of ion channels that control adrenal response to hypoglycemia
Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...
The EMBO Journal6d
Brain mitophagy in space and time
A new resource by Rappe et al (2024) now provides a spatiotemporal landscape of mitophagy changes during mouse brain aging at ...
The EMBO Journal7d
Liver DE(HP)toxification: luteolin as “phthalates-cleaner” to protect from environmental pollution
Environmental pollution is a major health problem that affects the health of individuals worldwide and is cumulative with ...
The EMBO Journal20d
RNA binding protein ZCCHC24 promotes tumorigenicity in triple-negative breast cancer
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Triple-negative breast cancer (TNBC) lacks the ...
The EMBO Journal9d
Sepsis-induced changes in pyruvate metabolism: insights and potential therapeutic approaches
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Sepsis is a heterogeneous syndrome resulting ...
The EMBO Journal7d
Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cancer cell plasticity contributes ...
The EMBO Journal16d
BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Both Wnt and BMP signaling regulate ...
The EMBO Journal12d
Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The solute carrier 17 (SLC17) family contains ...
The EMBO Journal9d
Ependymal cell lineage reprogramming as a potential therapeutic intervention for hydrocephalus
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Hydrocephalus is a common neurological ...
The EMBO Journal13d
A novel LRR receptor-like kinase BRAK reciprocally phosphorylates PSKR1 to enhance growth and defense in tomato
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. BRAK promotes tomato seedling growth, fruit ...