The San Francisco 49ers head into Week 4 with a 3-0 record but plenty of uncertainty. Injuries to Nick Bosa, Ricky Pearsall, Jauan Jennings, and others have forced the team to lean heavily on depth ...

Sunday, 4:05 p.m. EST, CBS. BetMGM NFL odds: Jaguars by 2 1/2. Against the spread: Cardinals 5-5, Jaguars 5-5. Series record: ...

The 49ers had horrendous luck last year, but their luck could change in 2021. From the looks of it, their schedule will be much easier next season than it was last season. Of course, it's impossible ...

The San Francisco 49ers may be getting a key piece of their offense back just in time for Week 4. Quarterback Brock Purdy, who has been sidelined with shoulder and toe issues, could be available to ...

The 49ers' quarterback room simply isn't good enough. Last season, they had Brock Purdy AND Sam Darnold. That was a good quarterback room. Darnold clearly pushed Purdy who had an MVP-caliber year in ...

The 49ers have proved they aren’t very good when Jimmy Garoppolo isn’t on the field. But Garoppolo has proved he has trouble staying on the field. Given that, the biggest news from Kyle Shanahan’s ...

Mike Florio believes the Minnesota Vikings might look to trade for San Francisco 49ers quarterback Mac Jones in the offseason ...