Understanding intrinsically disordered protein regions and their roles in cancer

Every function in a cell is associated with a particular protein or group of proteins, typically in a well-defined ...

Top 3 Biotech Stocks Capitalizing on the AI Revolution

Eli Lilly and Company, Novo Nordisk A/S, Relay Therapeutics Inc, Neumora Therapeutics Inc. Read 's Market Analysis on Investing.com ...
eLife

HSD17B7 is required for Auditory Function by Regulating Cholesterol Synthesis in Sensory Hair Cells

This study provides valuable data on the role of Hsd17b7, a gene involved in cholesterol biosynthesis, as a potential regulator of mechanosensory hair cell function. The authors used both zebrafish ...
The Manila Times

AEON Biopharma Reports Positive and Robust Biosimilarity Results: Identical Amino Acid Sequence and Highly Similar Functional Analysis Data

Strategic Implications: Analytical findings reported today underscore ABP-450’s potential to become the first full label therapeutic biosimilar to BOTOX® in the U.S., positioning AEON to address a >$3 ...
Technology Networks

An Introduction to Bioinformatics, Bioinformatics Tools and Applications

This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as ...
Phys.org

AI-guided analysis assigns amino acid-level roles in protein design

With a newly developed method that compares AI-generated protein sequences with naturally occurring ones, function- and structure-regulating amino acids can be determined much more precisely than ...
C&EN

Structure and Mechanism of the Pyridoxal 5′-Phosphate-Dependent Amino Acid γ-Substitution Enzyme in 6-Alkyl-Pipecolate Biosynthesis

CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China CAS Key ...
C&EN

From Alkylarenes to α-Amino Acid Derivatives via C-Difunctionalization

State Key Laboratory of Natural and Biomimetic Drugs, New Cornerstone Science Laboratory, Chemical Biology Center, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China ...