Precise calculations of binding free energy are pivotal in reducing the high costs and inefficiencies of drug discovery. A recent study presents PairMap, an innovative computational tool that ...

It probably hasn’t been long since you last slipped into something stretchy. From yoga pants to socks, stretch fabrics are ...

This important study characterizes the mechanics and stability of bolalipids from archaeal membranes using molecular dynamics simulations. A mesoscale model of bolalipids is presented and evaluated ...

Xinning Zhang and Ashley Maloney discovered that a geology technique shows promise in detecting cancer-like cells. If their ...

Here, the authors examine and compare the energy landscapes upon insertion of the gasdermin D and A3 monomers into an E. coli lipid extract bilayer using extensive atomistic molecular dynamics ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

If you are feeling drained, you may wonder how to increase your energy levels. You can get plenty of sleep, eat energizing foods, and exercise regularly to feel more energized. It's no wonder so ...

Incorporating both information theory and circuit perspectives, a new general energy consumption model is proposed to capture the energy consumption of channel decoder circuits. For the binary erasure ...

Angiotensin-II (Ang-II) infusion in mice has been used to model HTN induced end-organ dysfunction including ... we hypothesized that it would significantly alter the brain metabolic pathways involving ...

Constellation Energy, a major player planning to build extensive energy capacity for AI applications, saw its stock sink by more than 20 percent. This market reaction underscores a growing concern ...

Laboratoire de Biologie et Modélisation de la Cellule, CNRS, UMR 5239, Inserm, U1293, Université Claude Bernard Lyon 1, Ecole Normale Supérieure de Lyon, 46 Allée d’Italie, 69364 Lyon, France Centre ...

Lipid metabolism plays a crucial role in maintaining homeostasis and overall health, as lipids are essential molecules involved in bioenergetic processes. An increasing body of research indicates that ...