Head coach Kyle Shanahan of the San Francisco 49ers looks on during warmups before the game against the Arizona Cardinals at ...

San Francisco 49ers WR Skyy Moore sped past the Cardinals coverage unit with a 98-yard kickoff return to open the Week 11 ...

The Arizona Cardinals and San Francisco 49ers revealed their final inactives report for Week 11 - who's in, who's out?

The Arizona Cardinals will be without one of their top playmakers when they face the San Francisco 49ers this Sunday at State Farm Stadium. According to multiple reports, wide receiver Marvin Harrison ...

Mac Jones went 5-3 as the 49ers starting quarterback while Brock Purdy recovered from a turf toe injury. But his time as starter came to an end Sunday when coach Kyle Shanahan announced Purdy would ...

A big stretch of games begins for the San Francisco 49ers on Sunday in Arizona against the Cardinals. Here's how to watch ...

The 49ers and Saints, to completely different results, revealed the best way to stop the Rams' vaunted pass rush. It's called ...

Kyle Shanahan revealed that his wife made sure he gave Mac Jones his due praise after he filled in admirably for the 49ers at ...

Mac Jones filled in well as the 49ers' starting quarterback while Brock Pirdy has been out, but now he's headed back to the ...

The San Francisco 49ers are taking on the Arizona Cardinals on Sunday, and ahead of the game, they've made three ...

HC Kyle Shanahan recently said that they are hoping to start QB Brock Purdy in Week 11. Although Mac Jones has done well, ...

The San Francisco 49ers made a significant roster move that doesn't bode well for one of their top defensive players.