Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though ...

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss.

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category.

Researchers say study findings have important implications for our understanding of the pathogenesis of obesity and potential therapeutic applications.

Though a complex interplay of genes, diet, and environment contribute, 90% of cases share one thing in common: leptin resistance. In lean individuals, fat cells produce the hormone leptin ...