Opioids for breathlessness: a narrative review | BMJ Supportive ...
Chronic breathlessness is a disabling and distressing condition for which there is a growing evidence base for a range of interventions. Non-pharmacological interventions are the mainstay of management and should be optimised prior to use of opioid medication. Opioids are being implemented variably in practice for chronic breathlessness. This narrative review summarises the evidence defining ...
Management of hiccups in palliative care patients
Treatment algorithm for persistent and intractable hiccups in palliative care patients. PPI, proton pump inhibitor. If intractable hiccups are caused by a central type of condition, baclofen (level II) is recommended as first-line treatment. It is the only drug that …
Anticipatory prescribing in community end-of-life care: systematic ...
Background The anticipatory prescribing of injectable medications is recommended practice in controlling distressing symptoms in the last days of life. A 2017 systematic review found practice and guidance was based on inadequate evidence. Since then, there has been considerable additional research, warranting a new review. Aim To review the evidence published since 2017 concerning anticipatory ...
Impact of dementia on informal care: a systematic review of family ...
Introduction Caregivers play a major role in providing all the support and care in daily activities for their relatives with dementia. To fully describe the influence of dementia caregiving on family caregivers’ life, we conducted a systematic review including caregivers’ perceptions about the positive and negative aspects of caring and the expressed factors. Materials and methods We ...
Jun 18, 2020 · AbstrAct. Objective To engage young adults (18–35 years of age) with life- limiting neuromuscular conditions, their parents, and health and community providers in the development of a public health approach to palliative care. A public health approach protects and improves health and wellness, maximises the quality of life when health cannot ...
Single-arm clinical trials: design, ethics, principles
Jun 4, 2024 · Clinical trial staging. Single-arm trials are a commonly used clinical trial design that can be applied in all four phases of clinical trials. In the phase I clinical trials, single-arm trials are employed to investigate the mechanism of action, pharmacokinetic properties and safety of a new drug, providing foundational data for subsequent clinical trials.15 The phase II …
Breast cancer nursing interventions and clinical effectiveness: a ...
Methods Cochrane Controlled Register of Trials (CENTRAL), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medline and Embase databases were searched (January 1999 to May 2019) to identify randomised controlled trials (RCTs) and controlled before-and-after studies of interventions delivered by nurses with oncology …
Hydration and symptoms in the last days of life
Introduction. Most patients with a deteriorating chronic illness have a reduced oral intake at the end of life. This may be due to illness or treatment-related symptoms or complications, such as dysphagia, nausea or vomiting, generalised weakness and, in the last days of life, to a decreased level of consciousness or a loss of desire to drink.1 2 …
Homepage | BMJ Supportive & Palliative Care
BMJ Supportive & Palliative Care is a Plan S compliant Transformative Journal.. BMJ Supportive & Palliative Care holds an inclusive view of supportive and palliative care research and we are able to call on expertise to critique the whole range of methodologies within the subject, including those working in transitional research, clinical trials, …
End-of-life care quality measures: beyond place of death
Place of death. Place of death is widely used as a quality metric in end-of-life care policy in high-income countries.7–10 In policy it has been deployed in a range of ways: as a ‘vital sign’ focusing on the ‘proportion of all deaths that occur at home’25; as a focus on deaths in ‘usual place of residence’ (in residential, care and nursing homes); and more recently to assess ...