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MedLecturesMadeEasy
Phases of clinical trials
Preclinical: Laboratory & animal models Goal: Explore if & how new treatment may work Phase I: Small number (eg, 20-100) of healthy subjects Goal: Evaluate toxicity, maximum tolerated dose, adverse effects, pharmacokinetics & pharmacodynamics of new treatment (safety) Phase II: Small number (eg, up to a few hundred) of affected subjects Goal ...
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During an autopsy, a pathologist carefully dissects and examines organs, tissues, and fluids, collecting samples for further laboratory analysis. The information gathered from autopsies not only assists in understanding the circumstances surrounding a person's death but also aids in identifying potential risk factors and improving preventive measures for various diseases. It involves a systematic examination of organs and tissues, often providing valuable insights into disease progression and co
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