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Supplementing with vitamin D2 may actually lower levels of active vitamin D in the body. Supplementing with vitamin D2 reduced the primary circulating form of vitamin D3 by ~18 nmol/L (7 ng/mL), which is enough to move from sufficient to an insufficient range. This is due to the fact that vitamin D2 enhances the breakdown of vitamin D3 in the body. While vitamin D2 comes from plants and vitamin D3 comes from animal sources or sunlight, research consistently shows that D3 raises serum vitamin D l
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