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The OLIO clinical trial aims to find out if the addition of olaparib, or a combination of olaparib and durvalumab, given together with standard chemotherapy, can help to control cancer in pre-menopausal women with HR-positive, HER2-negative breast cancer. Young patients with HR-positive, HER2-negative breast cancer are often treated with hormone therapy and chemotherapy and have a 2-3x increased risk of breast cancer recurrence over their lifetime. It is believed that targeted treatments in addi
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